Added: Obadiah Miner - Date: 19.02.2022 12:17 - Views: 34327 - Clicks: 1356
Niacin vitamin B3 is promoted for rapidly clearing the body of drugs of abuse, such as cocaine and cannabis, and is alleged to interfere with urine drug screening. We present 4 cases of such novel use associated with ificant adverse effects. Two cases had isolated skin manifestations, whereas the other 2 presented with life-threatening manifestations, including nausea, vomiting, dizziness, hepatotoxicity, metabolic acidosis, and hypoglycemia evolving into hyperglycemia.
One patient also had profound neutrophilia and QT C -interval prolongation. All patients improved after cessation of the drug use and supportive treatment.
Health care providers should be aware of these potential adverse effects of niacin and of the misguided use of this vitamin by patients seeking to interfere with urine drug screening. Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article, that may create any potential conflict of interest.
The authors have stated that no such relationships exist. See the Manuscript Submission Agreement in this issue for examples of specific conflicts covered by this statement. View PDF. Access through your institution Purchase PDF. Author links open overlay panel Manoj K. Delgado MD d Kevin C. Add to Mendeley Share.
Recommended articles Citing articles 0. Supervising editor: Richard C. Dart, MD, PhD Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article, that may create any potential conflict of interest.
Publication dates: Available online April 5, Reprints not available from the authors. Published by Mosby, Inc. All rights reserved.
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Toxicity from the use of niacin to beat urine drug screening